There actually only minor differences between the Mac and the PC.  The most obvious annoyance with PC users on the MAC is the 1 button mouse.  However any PC user can connect their 2 button USB mouse into the MAC and negotiate the use.  Also another difference that annoys PC users is that on the MAC Xing out does not exit the program but only the page being used in the program.  It quickly becomes second nature to use keyboard combination apple Q to exit whichever program menu is on the screen.  The last difference is searching for a file through folders and sub folders which is really just like using the start menu in the PC.